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Lesson Seven: Obesogens

Module Three: The Obesogen Hypothesis


The following questions are meant to give you an idea of this module's main learning objectives.  If you feel comfortable answering the questions without reviewing your notes, then you are on your way to knowing the content of this module.

  • How do thiazolidinediones provide evidence that obesogens exist?
  • What are organotins?  Where can they be found?  How do they affect the endocrine system (in animals of all classes?)  What characteristics of organotins make them such a problem as obesogenic chemicals?
  • How does prenatal exposure to TBT the ability for an animal to become obese on a cellular level?  What specific evidence is there to support your answer?
  • What are MSCs, and how do they fit into the obesogen hypothesis?

Creative Thinking Challenges

  • Based on what you’ve learned in this course so far, in what specific ways can green chemistry be used to decrease obesogen entry into the environment?
  • Research one specific organotin and answer the following questions:
    • What is its name?
    • What is its use?
    • How does it enter the environment?
    • How pernicious is it in the environment?
    • Is it regulated by any agency in any fashion?
    • What effects does it have on living cells (or organisms, or animals.)

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